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Published:  November 14, 2011
 
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Slide 1: M&M Conference 9/9/08
Slide 2: M&M Conference        MM 78 y/o F presented with a 5 day hx of left lower quadrant pain and abdominal distention. Pt admittledly has chronic constipation, but noticed a recent increase in difficulty to defecate The patient did have a large bowel movement a day before presentation to the er After that BM she began to experience LLQ pain, at times “intense” Also, during the last 5 day she claimed to have lost her appetite Denied Nausea/Vomiting. Denied dysuria
Slide 3: M&M Conference PMHx- Recurrent diverticulitis, DM, HTN, Hyperlipidemia,  PSHx-Mastoidectomy, Appendectomy  Meds- Atenolol, Metformin  SHx-lives with daughter; denies alcohol, smoking, drugs  FHx- HTN, DM  Allergies-NKDA 
Slide 4: M&M Conference          Vitals – Tmax 36.4 P-87 BP-110/64 O2 sat-98 % RA GEN-AAOx3, No acute distress Skin- Poor skin turgor HEENT-PERRL , No Lymphadenopathy CVS-RRR Lung-CTAB, no rales, no rhonchi Abd- Soft, ND, LLQ tenderness, +BS – No rebound tenderness, No mass, minimal LLQ guarding Ext- L UE congenital deformity Rectal- Good tone, No stool, No blood
Slide 5: M&M Conference  Labs – Na 134 K 4.9 Cl 95 CO2 24 BUN 70 Crea 3.0 – Glu 157 AST 30 ALT 16 ALP 37 – WBC 4.8 Hgb 10.4 Hct 31.1 Plt-302
Slide 6: M&M Conference  Radiology – Free intraperitoneal air c/w bowel perforation – SBO secondary to inflammatory process due to acute diverticulitis
Slide 8: M&M Conference  A/P – – – – 78 y/o Female recurrent diverticulitis with localized tenderness no signs of diffuse abdominal tenderness Dehydration Aggressive fluid resuscitation NPO Serial abdominal exams Cipro, Flagyl  Plan – – – –
Slide 9: M&M Conference  HD #1     – 6 am – 12 pm Pt feels well LLQ pain resolving, Minimal residual tenderness No N/V, +Flatus Plan-cont NPO, serial abdominal exams, cont abx – – – – Mistakenly received CLD Lethargic, change in mental status Dyspnea, use of accessory muscle Abdomen  Marked distention  Increased tenderness in LLQ  Acute decompensation  Intubated at bedside  To OR for Exploration
Slide 10: M&M Conference    Post Op Dx- Acute Diverticulitis with free perforation Procedure- Exploratory Laparotomy/ Moblization of Splenic flexure/ Hartmann’s Procedure Details of Procedure – Feculant material found surrounding sigmoid colon – Perforation noted at center of sigmoid colon    Specimen- Descending and Sigmoid Colon EBL-100cc Complication- none
Slide 11: M&M Conference  Post Operative Course – POD#1  Increase Cardiac enzyme – Cardiology consulted  No urgent intervention- more related to overall condition and renal insufficiency opposed to obstructive disease – POD#4  Extubated progressing well  Transferred out of ICU  Later that evening – Atrial Fibrillation  Rate controlled started on Amiodarone, diltiazem  Transferred back to ICU
Slide 12: M&M Conference  POD#5 POD#7    – Stabilized – Rate controlled – Transferred back to floor – Stable Ostomy functioning well Remained afebrile ABX stopped POD#7   POD#9 – Discharged to Rehab facility – To follow Cardiology- anticoagulation
Slide 13: M&M Conference  Morbidity – Recurrent Diverticulitis with free perforation – Delay in Operative Intervention
Slide 14: Diverticulitis  Many controversies lie within the topic of diverticulitis – Conservative vs Operative – Operative intervention in acute setting vs. elective – When to Operate in younger pts – When or if to operate in older pts – Focus  What type of operative intervention does the literature support?
Slide 15: Diverticulitis Clinical presentations of diverticular disease range from asymptomatic diverticulosis, diverticulosis with periodic spasmodic abdominal pain and bloating, diverticulosis with hemorrhage, and finally, diverticulitis.  Two commonly utilized classifications of diverticulitis 
Slide 16: Diverticulitis  1) European Association for Endoscopic Surgeons developed a classification scheme based upon the severity of its clinical presentation – diverticulitis is divided into symptomatic uncomplicated disease, recurrent symptomatic disease, and complicated disease  2) Hinchey – In 1978, Hinchey and colleagues devised a staging system for grading the degree of perforation in diverticulitis  Use of radiologicand intra-operative findings
Slide 17: Hinchey Classification Stage I II III IV Description Pericolic or mesenteric abscess Walled off pelvic abscess Generalized purulent peritonitis Generalized fecal peritonitis
Slide 18: Diverticulitis  Operations are mainly reserved for cases of complicated diverticulitis – i.e., patients with perforation and peritonitis, abscess formation, fistula, or obstruction.  Although this may seem clear-cut, decisions regarding if and when to operate patients with diverticulitis remain a topic of significant debate.
Slide 19: Diverticulitis  Operation is clearly indicated when the patient presents with perforation and diffuse peritonitis, whether it is purulent or feculent (Hinchey stages III and IV). – However, the ideal surgical procedure in such cases of perforation remains a matter of debate.     simple washout of the abdomen with drainage resection with a Hartmann pouch primary resection with anastomosis with diverting ileostomy primary resection with anastomosis and no temporary stoma
Slide 20: Diverticulitis  Hartmann’s resection has proven to be a safe and effective approach, and is based upon the idea that an anastomosis in the setting of acute infection/inflammation is dangerous and associated with a high rate of suture line breakdown.
Slide 21: Diverticulitis  simple washout with drainage – paucity of data to support a minimalist, simple washout approach  there are only 18 case reports in the literature describing the technique and its results – Moderate success  Primary Anastomosis with and without diversion – Some evidence of low leak rate with primary anastomosis w/o ostomy  Questionable studies where patient status not evenly evaluated – Pt’s comorbidities not compared
Slide 22: Diverticulitis  Hartmann’s procedure vs Primary anastomosis with or without ostomy – Systematic literature review of 50 studies comparing a Hartmann’s procedure to a primary resection with anastomosis for perforated diverticulitis found 569 reported cases of primary anastomoses  mortality and morbidity in the patients with an anastomosis was the same as in the patients who underwent the Hartmann’s procedure – – – patient condition Comorbidites Not evenly facotred
Slide 23: Diverticulitis  Overall – There is intriguing data about the surgical management of acute diverticulitis,  But it must be viewed with caution, – especially in the case of toxic patients with multiorgan system failure and/or shock – Safest method  Perform a Hartmann’s procedure in the face of an acute perforated diverticulitis with perotionits – There is a viable argument to perform a primary ananstomosis even in the face of feculant contamination, especially in relatively healthy patients

   
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